A
storied Upper East Side residence, once the epicenter of writer George Plimpton's life and work, is set to hit the market for $5.25 million. The 4,700-square-foot duplex at 541 E. 72nd St., where Plimpton lived with his wife Sarah Dudley Plimpton for nearly six decades, offers a rare opportunity to own a piece of New York's cultural heritage.

    Built in 1894 as tenements, the building was transformed into elegant residences in the 1930s by architects Sacchetti & Siegal. The "Black and Whites" row houses, known for their distinctive two-tone facades and lipstick-red doors, have long been a hub of Manhattan's elite.

    The five-bedroom, 6.5-bath property boasts a quiet cobblestone enclave overlooking the East River, with 60 feet of river views and 40 windows that flood the space with natural light. The home has undergone contemporary upgrades while retaining its historic character, including three fireplaces adorned with mahogany mantels and intricate tilework.

    The duplex was once the site of legendary literary parties attended by figures like Truman Capote, Jacqueline Kennedy Onassis, and Paul McCartney. It also housed the Paris Review's offices, where Plimpton published early works by Jack Kerouac and Philip Roth, and featured interviews with literary titans like Ernest Hemingway.

    "True American icons have graced this home over the past six decades," says Whitney Mogavero, who represents the listing alongside Lisa Gustin. "From the literary elite to Who's Who of NYC society, this home has been a stage for cultural giants."

    The layout is as grand as its history, with a gracious foyer leading to a double living room and a kitchen equipped with high-end appliances. Upstairs, four bedrooms include a corner primary suite with built-ins and serene water views.

    The decision to sell comes as Sarah Plimpton relocates to Santa Fe, New Mexico, leaving the iconic residence ready for its next chapter.